Quick Answer: A major 2023 study in Nature Medicine found erythritol was associated with increased risk of heart attack, stroke, and blood clotting. However, erythritol occurs naturally in fruits and was previously considered one of the safest sugar alcohols. The debate is ongoing.
Erythritol is a sugar alcohol used as a zero-calorie sweetener in keto products, protein bars, "zero sugar" drinks, and stevia/monk fruit blends. It occurs naturally in small amounts in grapes, pears, and fermented foods. For years, it was considered the safest sugar alcohol — no glycemic impact, no digestive issues (unlike sorbitol/xylitol), and no effect on gut bacteria. Then in February 2023, a Cleveland Clinic study published in Nature Medicine found that people with the highest blood erythritol levels had double the risk of heart attack and stroke. The researchers found that erythritol enhanced platelet reactivity (blood clotting). However, critics noted the study was observational, the participants already had cardiovascular risk factors, and the erythritol levels measured may have been endogenously produced (by the body) rather than from dietary sources. More research is needed.
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The 2023 Nature Medicine study raised cardiovascular concerns, but erythritol has no calories and doesn't spike blood sugar. The cardiovascular risk findings need more research to confirm.
Truvia, Swerve, many keto/low-carb products, protein bars, sugar-free chocolate, zero-sugar drinks, and most stevia and monk fruit blends contain erythritol as a bulking agent.
CheckIt AI. (2026). "Is Erythritol Safe? — CheckIt AI". Climaverse PBC. Retrieved from https://getcheck.it/answers/is-erythritol-safe"Is Erythritol Safe? — CheckIt AI." CheckIt AI, Climaverse PBC, 2026-03-05. https://getcheck.it/answers/is-erythritol-safe.<a href="https://getcheck.it/answers/is-erythritol-safe">Is Erythritol Safe? — CheckIt AI — CheckIt AI</a>@misc{checkit2026answersiserythritolsafe,
title = {Is Erythritol Safe? — CheckIt AI},
author = {CheckIt AI},
year = {2026},
publisher = {Climaverse PBC},
url = {https://getcheck.it/answers/is-erythritol-safe},
note = {Retrieved 2026-03-05}
}