| Factor | Caramel Color (4-MEI) | Titanium Dioxide |
|---|---|---|
| E-Number | — | E171 |
| Category | Artificial Color | Artificial Color |
| Severity | Moderate Risk (6/10) | Moderate Risk (6/10) |
| FDA Status | FDA-approved. FDA states that a consumer would need to drink more than 1,000 cans of cola per day to reach 4-MEI doses s… | FDA-approved (21 CFR 73.575) at levels not exceeding 1% by weight of the food. FDA has not taken action to restrict desp… |
| EFSA Status | EFSA approved with specific 4-MEI limits. ADI varies by class: Class I and II have no specific ADI; Class III ADI 300 mg… | EFSA concluded in May 2021 that E171 could no longer be considered safe, citing inability to rule out genotoxicity of Ti… |
| Banned In | — | — |
| Products Found | 24 | 20 |
Both Caramel Color (4-MEI) and Titanium Dioxide have the same severity score (6/10). Neither is clearly worse than the other based on current data.
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CheckIt AI. (2026). "Caramel Color (4-MEI) vs Titanium Dioxide — Which Is Worse? | CheckIt AI". Climaverse PBC. Retrieved from https://getcheck.it/ingredients/caramel-color-vs-titanium-dioxide"Caramel Color (4-MEI) vs Titanium Dioxide — Which Is Worse? | CheckIt AI." CheckIt AI, Climaverse PBC, 2026-03-05. https://getcheck.it/ingredients/caramel-color-vs-titanium-dioxide.<a href="https://getcheck.it/ingredients/caramel-color-vs-titanium-dioxide">Caramel Color (4-MEI) vs Titanium Dioxide — Which Is Worse? | CheckIt AI — CheckIt AI</a>@misc{checkit2026ingredientscaramelcolorvstitaniumdioxide,
title = {Caramel Color (4-MEI) vs Titanium Dioxide — Which Is Worse? | CheckIt AI},
author = {CheckIt AI},
year = {2026},
publisher = {Climaverse PBC},
url = {https://getcheck.it/ingredients/caramel-color-vs-titanium-dioxide},
note = {Retrieved 2026-03-05}
}