Sucralose Side Effects

Sucralose is a artificial sweetener with 2 high-severity side effects. Found in 27 products in our database. FDA approved.

5
Known Side Effects
27
Products Contain It
2
High Severity
5
Safer Alternatives

What Is Sucralose?

Sucralose (Splenda) is an artificial sweetener 600x sweeter than sugar. Recent studies have raised concerns about DNA damage when heated and disruption of gut bacteria.

Also known as:
SplendaE955Trichlorogalactosucrose

Known Side Effects

High Risk Gut microbiome disruption
High Risk Genotoxicity (DNA damage) when heated
Moderate Glucose and insulin response changes
Moderate Digestive issues (bloating, gas, diarrhea)
Moderate Potential inflammatory effects

Regulatory Status

🇺🇸 FDA Status

FDA approved. ADI of 5mg/kg body weight.

🇪🇺 EU Status

Legal. EFSA-approved with ADI of 15mg/kg.

Scientific References

  1. Schiffman & Rother (2013) — Journal of Toxicology review
  2. Sucralose-6-acetate genotoxicity study (2023) — Journal of Toxicology and Environmental Health
  3. Studies showing altered gut microbiome composition

Products Containing Sucralose (27 found)

These products were found to contain sucralose or its variants in our database of 26,000+ grocery products.

#ProductBrandScore
1equate antacidUnknown4/100
2MAX PROTEIN NUTRITION SHAKE, MILK CHOCOLATEAbbott Laboratories Inc 7/100
3VANILLA FLAVORED LIGHT GREEK NONFAT YOGURT, VANILLAWal-Mart Stores, Inc.7/100
4Premier ProteinPremier Protein7/100
5Equate Antacid TabletsUnknown16/100
6TOASTED COCONUT VANILLA LIGHT GREEK NONFAT YOGURT, TOASTED COCONUT VANILLAWal-Mart Stores, Inc.20/100
7SPARKLING WATERCostco Companies Inc.24/100
8plant-based protein supplementEquate24/100
9CREAMY MILK CHOCOLATE MEAL REPLACEMENT SHAKE, CREAMY MILK CHOCOLATEWal-Mart Stores, Inc.24/100
10SKITTLES ORIGINAL PERFORMANCE ENERGY DRINKWoodbolt Distribution, LLC24/100
11Cookies & Cream Protein BarBarebells24/100
12CHOCOLATE CHIP COOKIE DOUGH PROTEIN BARS, CHOCOLATE CHIP COOKIE DOUGHQuest Nutrition, LLC24/100
13quest protein barQuest24/100
14Quest Protein BarQuest Overload Sunday24/100
15MIXED BERRY HYDRATION DRINK, MIXED BERRYWal-Mart Stores, Inc.59/100

Safer Alternatives to Sucralose

SteviaMonk fruit extractErythritolAlluloseRaw honey (in moderation)
📬

Get Your Free Weekly Clean Food Guide

Join health-conscious shoppers. Every week: worst products to avoid, cleanest new finds, and FDA recall alerts.

No spam. Unsubscribe anytime.

Scan Products for Sucralose Free →

Frequently Asked Questions

What are the side effects of sucralose?
Sucralose has been linked to gut microbiome disruption, DNA damage (especially when heated), glucose/insulin response changes, and digestive issues including bloating and diarrhea.
Is sucralose safe for cooking?
Studies show sucralose can break down into genotoxic compounds (sucralose-6-acetate) when heated. Many health experts recommend not using it in cooking or baking.

⚕️ Disclaimer: This information is for educational purposes only and is not medical advice. Side effect data is compiled from published scientific studies and regulatory assessments. Always consult your healthcare provider for personalized guidance. Last updated: 2026-03-05.

Other Ingredient Side Effects

Red 40 (Allura Red AC) Yellow 5 (Tartrazine) Yellow 6 (Sunset Yellow FCF) Red 3 (Erythrosine) Blue 1 (Brilliant Blue FCF) Blue 2 (Indigo Carmine) Aspartame Acesulfame Potassium (Ace-K) MSG (Monosodium Glutamate) High Fructose Corn Syrup (HFCS) All Ingredient Side Effects Banned in Europe Ingredient Encyclopedia
CheckIt AI
CheckIt AI
★★★★★ 4.7 · 202+ reviews

See what's really in your food

Scan any food label instantly. No barcode needed. 26,000+ products scored.

Download Free on the App Store →

Free · No credit card required · Works on iPhone & Android

Scanner Apps

Gluten Scanner AppDairy Scanner AppSeed Oil Scanner AppPeanut Allergy Scanner AppADHD Food Scanner AppIBS Food Scanner AppPregnancy Food Scanner AppCarnivore Diet Scanner AppKeto Scanner AppPaleo Scanner AppVegan Scanner AppCeliac Scanner AppMigraine Food Scanner AppKidney Diet Scanner AppCrohn's Food Scanner AppThyroid Scanner AppPCOS Food Scanner AppGout Food Scanner AppEczema Food Scanner AppToddler Food Scanner AppHeart Health Scanner AppAthlete Nutrition Scanner AppAcne Food Scanner AppFODMAP Scanner AppAIP Scanner AppMold Toxin Scanner AppHistamine Scanner AppOxalate Scanner AppNightshade Scanner AppSoy Scanner AppCorn Scanner AppEgg Allergy Scanner AppTree Nut Scanner AppShellfish Allergy Scanner AppSulfite Scanner AppSalicylate Scanner AppLectin Scanner AppSugar-Free Scanner AppLow Sodium Scanner AppMediterranean Diet Scanner AppWhole30 Scanner AppDiabetic Food Scanner AppColitis Food Scanner AppIC Food Scanner AppLupus Food Scanner AppHashimoto's Scanner AppEndometriosis Food Scanner AppAutoimmune Food Scanner AppBaby Formula Scanner AppPet Food Scanner AppSenior Nutrition Scanner AppOzempic Food Scanner AppWegovy Food Scanner AppMounjaro Food Scanner AppUltra-Processed Food ScannerHalal Food Scanner AppKosher Food Scanner AppAnti-Inflammatory Scanner AppCandida Diet Scanner AppSIBO Food Scanner AppLeaky Gut Scanner AppCholesterol Food Scanner AppBlood Pressure Scanner AppWeight Loss Food Scanner AppPesticide Food Scanner AppHeavy Metal Scanner AppPFAS Food Scanner AppBreastfeeding Food Scanner AppAutism Food Scanner AppFertility Food Scanner AppGAPS Diet Scanner AppElimination Diet Scanner AppLow Carb Scanner AppNanny Food Scanner AppGrocery Store Scanner AppFood Allergy Scanner AppDye-Free Food Scanner AppMuscle Building Scanner AppMarathon Runner Scanner AppKids Food Scanner AppFood Sensitivity Scanner AppClean Label Scanner AppFSA/HSA Food Scanner AppWhole Food Scanner AppDog Food Scanner AppCat Food Scanner App

Ingredient Safety

Red 40Yellow 5Yellow 6AspartameBHABHTSodium NitriteCarrageenanSucraloseTitanium DioxidePotassium BromateHigh Fructose Corn SyrupMSGSodium BenzoateTBHQPolysorbate 80Red 3Caramel ColorSoy LecithinNatural FlavorsAcesulfame-KMaltodextrinXanthan GumGuar GumCitric AcidErythritolBlue 1Propyl GallateMono & DiglyceridesPectinAcacia GumAgarAnnattoAutolyzed YeastAzodicarbonamideBVOCalcium PropionateCarnauba WaxCelluloseDATEMDisodium InosinateGellan GumKonjacLocust Bean GumMethylcelluloseSodium AlginateSodium Aluminum PhosphateTragacanth Gum

Food Safety Answers

Is Red 40 Banned in Europe?What Foods Have Seed Oils?Is Carrageenan Safe?Worst Food AdditivesIs BHA Safe?Does Gatorade Have Food Dye?Titanium Dioxide in FoodIs Aspartame Safe?Is Sodium Nitrite Dangerous?Is MSG Bad for You?What Is HFCS?Is Sucralose Safe?Food Dye Banned in Europe?Is Potassium Bromate Banned?What Is Natural Flavors?Is Soy Lecithin Bad?Is Maltodextrin Bad?Is Xanthan Gum Safe?Is Red 3 Banned?Is TBHQ Bad?Foods Banned in Other CountriesIs Citric Acid Bad?What Is Polysorbate 80?Is Caramel Color Safe?Is Palm Oil Bad?What Is Cellulose in Food?Is Acesulfame-K Safe?Is Erythritol Safe?Is Guar Gum Safe?Is Food in America Safe?Cheerios & PesticidesBest Food Scanner AppHow to Read Food LabelsIs Yellow 5 Safe?Are Preservatives Bad?Artificial Sweetener SafetyIs Canola Oil Bad?Hidden Names for SugarFoods That Cause InflammationIs Annatto Safe?Is Azodicarbonamide Safe?Is Calcium Propionate Safe?Is Carnauba Wax Safe?Is Gelatin Halal?Is Locust Bean Gum Safe?Mono & Diglycerides SafetyIs Pectin Safe?Propylene Glycol in FoodWhat Is Agar Agar?What Is BVO?What Is DATEM?What Is Sodium Alginate?What Is Sodium Benzoate?

Cleanest Rankings

Cleanest Protein BarsCleanest CerealCleanest YogurtCleanest ChipsCleanest SnacksCleanest BreadCleanest SaucesCleanest JuiceCleanest CookiesCleanest CandyCleanest Ice CreamCleanest PastaCleanest Baby FoodCleanest Energy DrinksCleanest Protein PowderCleanest Frozen MealsCleanest CondimentsCleanest SodaCleanest Pet Food

Free-From Finder

Protein Bars Without Seed OilsCereal Without Artificial ColorsSnacks Without PreservativesYogurt Without Artificial SweetenersChips Without Seed OilsCookies Without Artificial ColorsCandy Without Artificial ColorsSoda Without Artificial SweetenersFrozen Meals Without MSGBaby Food Without SugarEnergy Drinks Without SweetenersProtein Bars Without SweetenersSnacks Without Seed OilsCereal Without SugarBread Without PreservativesIce Cream Without CarrageenanPasta Without Gluten

Store Scan Results

Costco Protein Bars RankedWalmart Cereal RankedTarget Snacks RankedWhole Foods Yogurt RankedKroger Bread RankedAldi Snacks RankedCostco Snacks RankedWalmart Chips RankedTarget Cookies RankedTrader Joe's Snacks RankedWhole Foods Bread RankedWalmart Juice RankedTarget Cereal RankedWalmart Bread RankedKroger Snacks RankedAldi Cereal RankedWhole Foods Snacks RankedKroger Cereal RankedAldi Bread RankedTrader Joe's Cereal RankedCostco Bread Ranked

Ingredient Comparisons

Red 40 vs Yellow 5Red 40 vs Yellow 6Aspartame vs SucraloseAspartame vs HFCSBHA vs BHTRed 40 vs AspartameCarrageenan vs Soy LecithinSucralose vs HFCSTBHQ vs BHATBHQ vs BHTRed 40 vs Titanium DioxideRed 40 vs Caramel ColorMSG vs Natural FlavorsSodium Benzoate vs Potassium BromateYellow 5 vs Red 3Polysorbate 80 vs CarrageenanXanthan Gum vs Guar GumRed 40 vs Red 3Erythritol vs SucraloseMaltodextrin vs HFCSAll Ingredient Comparisons

Store Reports

Walmart Report CardTarget Report CardCostco Report CardKroger Report CardWhole Foods Report CardTrader Joe's Report CardAldi Report CardSam's Club Report Card

Original Research

All Research StudiesGrocery Product Safety StudySeed Oil CensusSafest Grocery StoresSchool Lunch Safety ReportMost Common AdditivesBanned Ingredients in US Products

App Comparisons

CheckIt vs YukaCheckIt vs EWGCheckIt vs FooducateCheckIt vs MyFitnessPalCheckIt vs Think DirtyCheckIt vs FigCheckIt vs SooseeCheckIt vs NoomYuka vs EWGYuka vs Fooducate

Category Safety Reports

All CategoriesSnacks Safety ReportFrozen Foods SafetySweet Snacks ReportDesserts Safety ReportMeals Safety ReportBiscuits & CrackersChips Safety ReportCereals Safety ReportSalty Snacks ReportPlant-Based SafetyBeverages Safety

Store × Category Rankings

Walmart Snacks RankedCostco Snacks RankedTarget Snacks RankedWalmart Cereals RankedCostco Frozen FoodsTarget Desserts RankedWhole Foods SnacksTrader Joe's SnacksALDI Snacks RankedKroger Cereals Ranked

Worst & Best Rankings

Worst CandyWorst ChipsWorst SnacksWorst CerealsWorst Frozen FoodsBest SnacksBest CerealsBest Frozen FoodsBest Plant-BasedBest Desserts

Recipe & Meal Guides

All Recipe GuidesGluten-Free BreakfastGluten-Free SnacksDairy-Free DinnerVegan SnacksKeto BreakfastSeed Oil-Free SnacksGluten-Free Dairy-Free SnacksGluten-Free Soy-Free SnacksGF + DF + SF SnacksVegan Gluten-Free SnacksTop 8 Allergen-Free SnacksGF Snacks Without Seed OilsDairy-Free Nut-Free BreakfastGF DF EF Desserts

Store Allergy Guides

GF + DF Snacks at WalmartGF + DF Snacks at CostcoGF + DF Snacks at KrogerGF + DF Snacks at TargetGF + DF Snacks at ALDINut-Free Snacks at WalmartNut-Free Breakfast at CostcoVegan GF Dinner at KrogerDF + SF Lunch at WalmartGF + DF + SF at CostcoTop 8 Free at KrogerSeed Oil Free + GF at Walmart

Brand Report Cards

All Brand ReportsNestlé Safety ReportKellogg's Safety ReportGeneral Mills ReportPringles Safety ReportHaribo Safety ReportMission Foods ReportDoritos Safety ReportCheetos Safety ReportOreo Safety ReportLay's Safety Report

Safe for Conditions

All Condition GuidesIBS-Safe SnacksGERD-Safe DrinksDiabetic-Friendly BreakfastCeliac-Safe SnacksLow-Histamine DinnerADHD-Friendly SnacksAutoimmune BreakfastMigraine-Safe SnacksCrohn's-Safe SnacksEczema-Safe SnacksPCOS-Friendly Breakfast

Store Diet Guides

GF Snacks at WalmartVegan Snacks at WalmartKeto Protein Bars at CostcoGF Snacks at CostcoVegan Snacks at Trader Joe'sGF Cereal at Trader Joe'sDF Snacks at TargetLow Sugar Cereal at KrogerPaleo Snacks at Whole FoodsGF Snacks at ALDI

Diet Product Finder

All Diet ProductsKeto Energy DrinksVegan Protein BarsGluten-Free CerealLow Sugar CookiesDairy-Free Ice CreamPaleo JerkySeed Oil-Free ChipsNut-Free Granola BarsGluten-Free BreadVegan Chocolate

Banned in Europe

All Banned IngredientsRed 40 (Allura Red)Yellow 5 (Tartrazine)Yellow 6 (Sunset Yellow)Red 3 (Erythrosine)Titanium DioxideBHABHTPotassium BromateBrominated Vegetable OilAzodicarbonamideTBHQ

Store Rankings

All Store RankingsWorst Snacks at WalmartWorst Cereal at CostcoWorst Candy at TargetBest Snacks at WalmartBest Snacks at CostcoBest Snacks at Trader Joe'sBest Cereal at Whole FoodsBest Yogurt at TargetWorst Chips at KrogerBest Bread at ALDI

GLP-1 Friendly Foods

All GLP-1 Friendly FoodsGLP-1 Protein BarsGLP-1 YogurtGLP-1 SnacksGLP-1 CerealGLP-1 JerkyGLP-1 Protein Bars at WalmartGLP-1 Snacks at CostcoGLP-1 Yogurt at Trader Joe'sGLP-1 Cereal at Target

Hidden Ingredient Names

All Hidden NamesHidden Names for MSGHidden Names for SugarHidden Names for HFCSHidden Names for Food DyesHidden Names for SoyHidden Names for Trans FatHidden Names for GlutenHidden Names for DairyHidden Names for Seed OilsHidden Names for Palm Oil

Reformulation Tracker

All ReformulationsFanta Orange ChangesMountain Dew ChangesKraft Mac & CheeseCheerios ChangesGatorade ChangesPepsi ChangesTrix Cereal ChangesSubway Bread Changes

Food Safety by Age

All Age GuidesToddler-Safe SnacksBaby-Safe BreakfastKids-Safe SnacksKids-Safe LunchPregnancy-Safe SnacksPregnancy-Safe BreakfastSenior-Friendly SnacksAthlete SnacksNursing-Safe DrinksTeen-Safe Snacks

Ultra-Processed Rankings

All UPF RankingsMost Processed SnacksMost Processed CerealsMost Processed CandyMost Processed ChipsMost Processed Frozen FoodsUPF Snacks at WalmartUPF Cereal at CostcoUPF Chips at TargetUPF Candy at Walmart

Cleanest Brands

All Cleanest BrandsCleanest Snack BrandsCleanest Cereal BrandsCleanest Chip BrandsCleanest Cookie BrandsCleanest Yogurt BrandsCleanest Bread BrandsCleanest Baby Food BrandsCleanest Protein Bar BrandsCleanest Frozen Food Brands

Ingredient Side Effects

All Side EffectsRed 40 Side EffectsYellow 5 Side EffectsAspartame Side EffectsSucralose Side EffectsMSG Side EffectsBHA Side EffectsSodium Benzoate Side EffectsCarrageenan Side EffectsHFCS Side EffectsCaramel Color Side Effects

Brand Exposure Reports

All Brand ReportsNestlé ExposedKellogg's ExposedGeneral Mills ExposedFrito-Lay ExposedKraft ExposedCoca-Cola ExposedPepsi ExposedMars ExposedMondelēz Exposed

Guides & Tools

Download CheckIt AIUser ReviewsFood RecallsBanned in EuropeFood Safety ReportIngredient GlossaryStore RankingsIngredient EncyclopediaHealthier Swap FinderOur MethodologyIngredient ComparisonsTopic GuidesAll Food Safety AnswersOpen DataWhat's Really In Your Food
4.7
from 202+ ratings on the App Store
📋 Cite This Data
APACheckIt AI. (2026). "Sucralose Side Effects — Health Risks, FDA Status & Products | CheckIt AI". Climaverse PBC. Retrieved from https://getcheck.it/side-effects/sucralose
MLA"Sucralose Side Effects — Health Risks, FDA Status & Products | CheckIt AI." CheckIt AI, Climaverse PBC, 2026-03-05. https://getcheck.it/side-effects/sucralose.
HTML Embed<a href="https://getcheck.it/side-effects/sucralose">Sucralose Side Effects — Health Risks, FDA Status & Products | CheckIt AI — CheckIt AI</a>
BibTeX@misc{checkit2026sideeffectssucralose, title = {Sucralose Side Effects — Health Risks, FDA Status & Products | CheckIt AI}, author = {CheckIt AI}, year = {2026}, publisher = {Climaverse PBC}, url = {https://getcheck.it/side-effects/sucralose}, note = {Retrieved 2026-03-05} }